|
KMID : 1159320180200040589
|
|
Korean Journal of Vision Science
2018 Volume.20 No. 4 p.589 ~ p.596
|
|
|
Comparison of Intraocular Pressure Values of Normotensive and Glaucomatous Rats Using Two Types of Tonometers
|
|
Choy Yoon-Jung
Choi Jee-Hyun
|
|
|
Abstract
|
|
|
Purpose : We compared intraocular pressure (IOP) values measured by two types of tonometers in condition of normotensive and glaucomatous rat model. We tried to determine which of tonometer can more easily and accurately measure the IOP of animal model.
Methods : Glaucomatous eyes were induced by intracameral injections of hyaluronic acid in right eyes of six-week-old male Spargue-Dawley (SD) rats. Normotensive contralateral eyes were left eyes of the SD rats. IOP was measured using a rebound tonometer (Tonolab) and a immersive tonometer (Tonopen® XL) about 3:00 pm.
Results : The mean IOP values of normotensive control eyes were 10.80 ± 1.03 mmHg by Tonopen, and 15.10 ± 0.73 mmHg by Tonolab. They were statistically insignificant (p = .1). The mean IOP values of glaucomatous experimental eyes were 30.20 ± 2.67 mmHg by Tonopen, and 37.90 ± 2.73 mmHg by Tonolab. They were statistically insignificant (p = .95). High IOP values of glaucomatous eyes by two types of tonometers had strong positive correlation each other (r = .904, p < .01).
Conclusion : This is the first study to compare IOP values using two types of tonometers between normotensive and glaucomatous model made by intracameral injection of hyaluronic acid. Tonopen should be used carefully when the IOP is within normal range, and both Tonopen and Tonolab can be used reliably when the IOP is high.
|
|
|
KEYWORD
|
|
|
Normotensive and glaucomatous rat model, Hyaluronic acid, Tonolab, Tonopen
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|